What is the best over the counter medicine to dry up sinus?

3. Oral antihistamines, the non-sedating ones. To avoid feeling sleepy with your meds, go for the non-sedating options. Three are available over the counter: Claritin (loratadine), Allegra (fexofenadine), Zyrtec (cetirizine), and then there is the expensive prescription-only Xyzal.

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