Treatment of sodium nitroprusside overdose includes the following: Discontinuing sodium nitroprusside administration. Buffering the cyanide by using sodium nitrite to convert haemoglobin to methaemoglobin as much as the patient can safely tolerate. Infusing sodium thiosulfate to convert the cyanide to thiocyanate.
Similarly, you may ask, what is thiocyanate level?
Thiocyanate Level to Become Mailout Test. Measurement of thiocyanate levels is used to monitor patients who are receiving continuous infusions of nitroprusside (Nipride), a vasodilator used in the ICU setting. Nitroprusside is metabolized to cyanide and thiocyanate.
How toxic is cyanide?
In large doses, the body's ability to change cyanide into thiocyanate is overwhelmed. Large doses of cyanide prevent cells from using oxygen and eventually these cells die. The heart, respiratory system and central nervous system are most susceptible to cyanide poisoning.
What is SCN chemical name?
Thiocyanate (also known as rhodanide) is the anion [SCN]−. It is the conjugate base of thiocyanic acid. Common derivatives include the colourless salts potassium thiocyanate and sodium thiocyanate. Organic compounds containing the functional group SCN are also called thiocyanates.
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