What can cause large red blood cells?

There are multiple causes of enlarged red blood cells, which is termed macrocytosis, and most of them are easily corrected. Two of the most common causes are deficiencies in vitamin B12 and folic acid, which are frequently associated with anemia, as well.

Accordingly, what causes red blood cells to be larger than normal?

Anemia can be divided into different types based on the volume of the red blood cells. Macrocytic anemia means that the red blood cells are larger than normal. In microcytic anemia, the cells are smaller than normal. The most common causes of macrocytic anemia are vitamin B-12 and folate deficiency.

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