Do antihistamines make you tired?

Drowsiness is one of the major side effects of some antihistamines, such as diphenhydramine (Benadryl) and doxylamine succinate (the antihistamine found in Nyquil). And because of their powerful sedating qualities, antihistamines are also the active ingredients found in numerous over-the-counter sleep aids.

What is the best non drowsy allergy medicine?

Like Claritin, Zyrtec and Alavert, Allegra is among the second-generation antihistamines, which means that unlike older meds such as diphenhydramine (Benadryl) and chlorphiniramine (Advil Allergy Sinus, Singlet), they won't make you drowsy. But determining which one works best for you may take a little trial and error.

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